Drug intelligence / Profile preview

DR-102

Development stage
Phase 1
Lead developer
Teva Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

**DR-102** is an investigational 28-day combined oral contraceptive regimen developed by Teva. Each cycle consists of 21 days of desogestrel 0.15 mg plus ethinyl estradiol 0.02 mg tablets, followed by 7 days of ethinyl estradiol 0.01 mg tablets. Desogestrel is a progestin prodrug whose active metabolite, etonogestrel, provides progestogenic feedback that suppresses ovulation; ethinyl estradiol provides estrogenic activity and cycle control. DR-102 was evaluated in completed Phase 3 studies for prevention of pregnancy and in studies of ovarian follicular activity, hormone levels, and hemostatic parameters.

Other names
desogestrel + ethinyl estradioldesogestrel/ethinyl estradiol
02

Targets

ER (Estrogen receptor)PR (Progesterone receptor)

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