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Dr. Böhm Omega 3 complex
- Development stage
- Unknown
- Lead developer
- Medical University of Vienna
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Dr. Böhm Omega 3 complex is a dietary supplement containing concentrated omega-3 fatty acids, primarily eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). In a clinical study led by the Medical University of Vienna, this formulation was investigated for its systemic absorption and subsequent presence in tear fluid, measured via mass spectrometry on Schirmer's test strips. The therapeutic rationale for using omega-3 fatty acids in dry eye syndrome (DES) lies in their ability to modulate inflammatory pathways. They act as ligands for the G protein-coupled receptor GPR120 (FFAR4), which triggers anti-inflammatory signaling, and they competitively inhibit the metabolism of arachidonic acid by cyclooxygenase (COX) and lipoxygenase (LOX) enzymes. This results in a reduction of pro-inflammatory eicosanoids and an increase in specialized pro-resolving mediators (SPMs), ultimately improving tear film stability and reducing ocular surface damage.
- Brand names
- Dr. Böhm Omega 3 complex
- Other names
- omega-3 fatty acidsomega3 fatty acidsomega 3 fatty acidsfish oileicosapentaenoic aciddocosahexaenoic acidEPADHA
02
Targets
FFAR4 (Free fatty acid receptor 4)
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