Drug intelligence / Profile preview

Dropyal Evo

Development stage
Unknown
Lead developer
Bruschettini
Modality
Small Molecules
Administration
Ophthalmic
01

Overview

Dropyal Evo is a preservative-free, sterile ophthalmic solution developed by Bruschettini for the treatment of alterations of the ocular surface, such as dry eye disease and corneal epithelial damage. It is a fixed-dose combination containing 0.15% high molecular weight sodium hyaluronate and 0.01% cyanocobalamin (Vitamin B12), formulated with glycerin and sorbitol. Sodium hyaluronate acts as a lubricant and humectant, binding to CD44 receptors on corneal epithelial cells to promote cell migration, barrier protection, and wound healing. Cyanocobalamin provides antioxidant, anti-inflammatory, and neuroprotective effects, protecting ocular tissues from oxidative stress and facilitating corneal nerve regeneration and re-epithelialization. The formulation is designed to restore the homeostasis of the ocular surface and is compatible with contact lenses.

Brand names
Dropyal Evo
Other names
cyanocobalamin + sodium hyaluronatesodium hyaluronate + cyanocobalaminsodium hyaluronate + vitamin B12vitamin B12 + sodium hyaluronate
02

Targets

CD44 (CD44 antigen)

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