Drug intelligence / Profile preview

DS-01

Development stage
Phase 2
Lead developer
Seed Health
Modality
Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration
Oral
01

Overview

DS-01 is a multi-strain synbiotic developed by Seed Health, designed to support gastrointestinal and systemic health. It contains a proprietary blend of 24 probiotic strains across 12 species, including *Lactobacillus* and *Bifidobacterium*, paired with a non-fermentable prebiotic (punicalagins) derived from Indian pomegranate. The product utilizes a specialized capsule-in-capsule delivery system (ViaCap) to ensure the live microorganisms survive transit through the stomach and reach the colon. DS-01 is being investigated in clinical trials for its impact on fecal metagenomic stability, gut barrier integrity, and symptoms of irritable bowel syndrome (IBS), particularly the constipation-predominant (IBS-C) and mixed (IBS-M) subtypes.

Brand names
Seed DS-01 Daily Synbiotic
Other names
Seed Daily SynbioticDS-01 SynbioticDS01 SynbioticDS 01 Synbiotic

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