DS21150768

DS21150768: sourced facts only. name: "Here, we present the identification and pharmacological evaluation of DS21150768, a potent small-molecule HPK1 inhibitor with a novel chemical scaffold." [PMID:37944847]; target: "Here, we present the identification and pharmacological evaluation of DS21150768, a potent small-molecule HPK1 inhibitor with a novel chemical scaffold." [PMID:37944847]; developer: "Daiichi Sankyo Co., Ltd., Tokyo, 140-8710, Japan. Electronic address: [email protected]." [PMID:37944847]; modality: "Here, we present the identification and pharmacological evaluation of DS21150768, a potent small-molecule HPK1 inhibitor with a novel chemical scaffold." [PMID:37944847]; stage: "We conducted a comparison of the anti-tumor efficacy of DS21150768 alone or in combination with anti-PD-1 antibody in 12 different mouse cancer cell models, and observed that the treatments suppressed tumor growth in multiple models." [PMID:37944847]