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DSP-1083
- Development stage
- Unknown
- Lead developer
- Sumitomo Pharma
- Modality
- Cell Therapies
- Administration
- Intracranial (stereotactic Implantation)
01
Overview
**DSP-1083** is an investigational cell therapy for Parkinson’s disease composed of human induced pluripotent stem cell (iPSC)-derived dopaminergic progenitor cells. The primary mechanism is to restore dopaminergic neuronal function by implantation of dopamine neural progenitors, which secrete dopamine, aiming to ameliorate neurological symptoms of Parkinson’s disease. The therapy is currently under clinical development, with safety, tolerability, and efficacy being assessed in a first-in-human, multicenter trial. The sponsor and primary developer is Sumitomo Pharma America. Clinical administration involves stereotactic implantation into the brain[1][2][4][5][6].
- Brand names
- DSP-1083DSP1083DSP 1083
- Other names
- iPSC-derived dopaminergic progenitorsiPS cell-derived DA progenitorsinduced pluripotent stem cell-derived dopaminergic progenitors
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