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DSP-Visulex
- Development stage
- Unknown
- Lead developer
- Aciont
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Administration
- Ophthalmic, Topical
01
Overview
DSP-Visulex is a proprietary ophthalmic formulation of dexamethasone sodium phosphate delivered via the Visulex-P (passive) non-invasive drug delivery system. Developed by Aciont, Inc., it is specifically designed for the treatment of non-infectious anterior uveitis. The system utilizes a 5-minute topical application to deliver high concentrations (8% or 15%) of the corticosteroid, allowing for a significantly reduced dosing frequency—typically twice in the first week followed by weekly applications—compared to standard daily eye drops. Clinical Phase 1/2 data indicates that DSP-Visulex provides efficacy comparable to daily 1% prednisolone acetate drops with a favorable safety and tolerability profile.
- Brand names
- Visulex
- Other names
- Dexamethasone Sodium Phosphate VisulexVisulex-PVisulex-passive system
02
Targets
GR (Glucocorticoid receptor)
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