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DT3cP-Hib-MCV4 combined vaccine
- Development stage
- Unknown
- Lead developer
- CanSino Biologics
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
DT3cP-Hib-MCV4 is a hexavalent combination vaccine developed by **CanSino Biologics** (specifically through its subsidiary Cansino (Beijing) Biotechnology). The vaccine is designed to provide simultaneous protection against several major pediatric bacterial infections: diphtheria, tetanus, pertussis (whooping cough), *Haemophilus influenzae* type b (Hib) disease, and meningococcal disease caused by serogroups A, C, W, and Y. The pertussis component is a three-component acellular formulation (3cP), typically consisting of pertussis toxoid, filamentous hemagglutinin, and pertactin. By combining these antigens into a single injection, the vaccine aims to simplify pediatric immunization schedules and improve compliance. It is currently in Phase 1 clinical development.
- Other names
- Diphtheria, Tetanus, Pertussis (3-component acellular), Haemophilus influenzae type b, and Meningococcal (Groups A, C, W, Y) Conjugate Combined VaccineHexavalent DTaP-Hib-MCV4 Vaccine
02
Targets
NmA CPS (Neisseria meningitidis group A capsular polysaccharide)T-cell receptor / MHC class II-presented carrier-derived peptide complexPRN (Pertactin)Group Y CPS (Neisseria meningitidis group Y capsular polysaccharide)Neisseria meningitidis group C capsular polysaccharideFHA (Filamentous hemagglutinin)MenW CPS (Neisseria meningitidis serogroup W capsular polysaccharide)TT (Tetanus toxoid)
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