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DTaP-Hib-MCV4 vaccine (also referred to as DTcP-Hib-MCV4 Combined Vaccine) is an investigational pentavalent combination vaccine developed by CanSino Biologics. It is designed to simultaneously protect healthy children aged 2 months to 6 years against five major infectious diseases: diphtheria, tetanus, pertussis (whooping cough), Haemophilus influenzae type b (Hib) infections, and meningococcal meningitis caused by serogroups A, C, Y, and W135. The vaccine is formulated by combining acellular pertussis antigens (components), diphtheria and tetanus toxoids, a Hib polysaccharide conjugate, and a quadrivalent meningococcal conjugate (MCV4) based on CanSinoBIO's commercialized Menhycia® vaccine. By combining these components, the vaccine aims to reduce the number of required injections, improving vaccination compliance and efficiency. It is currently in Phase I clinical development in China.
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