Drug intelligence / Profile preview

DTwP-HepB-Hib-IPV(Sabin)

Development stage
Preclinical
Lead developer
Techinvention Lifecare
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

DTwP-HepB-Hib-IPV(Sabin) is a hexavalent combination vaccine being developed by Techinvention Lifecare. It is designed to provide protection against six major childhood diseases: diphtheria, tetanus, pertussis (whooping cough), hepatitis B, Haemophilus influenzae type b (Hib) disease, and poliomyelitis. The vaccine formulation includes diphtheria toxoid, tetanus toxoid, whole-cell Bordetella pertussis (wP) antigens, hepatitis B surface antigen, Haemophilus influenzae type b conjugate, and inactivated poliovirus based on Sabin strains (sIPV). By combining these six antigens into a single injection, the vaccine aims to simplify immunization schedules, improve compliance, and reduce the logistical burden on healthcare systems in developing regions. It is currently in the preclinical development stage.

Other names
Hexavalent combination vaccine (Techinvention Lifecare)diphtheria + tetanus + whole-cell pertussis + hepatitis b + haemophilus influenzae type b + inactivated poliovirus (Sabin)
02

Targets

HBsAg (Hepatitis B surface antigen)PRR (Pattern recognition receptors)Diphtheria toxinpMHC–TCR (Peptide–MHC–T-cell receptor complex)

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