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DTX-102 is a preclinical-stage bispecific antibody being developed by Dualitas Therapeutics (formerly Dual Therapeutics) for the treatment of autoimmune diseases, including arthritis. The drug is one of the lead programs utilizing the company's proprietary 'E1' Proximity Engager mechanism. This mechanism is designed to bring specific molecular targets into proximity to modulate immune responses, although the exact biological targets for DTX-102 have not been publicly disclosed. As of early 2024, the program is in the lead generation and optimization phase of preclinical development.
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