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Dual Checkpoint Agonist x Antagonist

Development stage
Preclinical
Lead developer
Radiant Biotherapeutics
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration
Intravenous, Subcutaneous
01

Overview

The Dual Checkpoint Agonist x Antagonist is a preclinical-stage therapeutic program developed by Radiant Biotherapeutics using its proprietary Multabody™ platform. This multi-specific engineered molecule is designed to modulate the immune system by simultaneously acting as an agonist at one immune checkpoint receptor and an antagonist at another. By leveraging the high-avidity and multi-targeting capabilities of the Multabody™ architecture, the drug aims to provide a sophisticated approach to immune regulation for the treatment of various immunological and inflammatory diseases. The specific checkpoint targets and lead indications within the immunology space remain undisclosed.

Other names
Checkpoint Agonist x Antagonist MultabodyDual Checkpoint Agonist x Antagonist (Radiant Biotherapeutics)

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