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The Dual Checkpoint Agonist x Antagonist is a preclinical-stage therapeutic program developed by Radiant Biotherapeutics using its proprietary Multabody™ platform. This multi-specific engineered molecule is designed to modulate the immune system by simultaneously acting as an agonist at one immune checkpoint receptor and an antagonist at another. By leveraging the high-avidity and multi-targeting capabilities of the Multabody™ architecture, the drug aims to provide a sophisticated approach to immune regulation for the treatment of various immunological and inflammatory diseases. The specific checkpoint targets and lead indications within the immunology space remain undisclosed.
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