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Dualase is a proprietary gene editing platform developed by Specific Biologics. It utilizes a novel double-cutter nuclease design that enables precise and efficient DNA editing by creating two targeted cuts in the genome. This approach allows for both precise DNA deletions (to disrupt genes) and increased repair (to correct genes), leveraging the cell’s natural DNA repair pathways. The technology aims to address genetic mutations that are not easily targeted with existing gene editors, offering potential advantages in specificity and therapeutic outcomes. Preclinical development is focused on diseases such as cystic fibrosis, as well as conditions affecting the liver, eyes, and central nervous system[2][6][8][10].
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