dulaglutide + biguanides

**dulaglutide + biguanides** is a combination therapy used in the management of type 2 diabetes. Dulaglutide is a glucagon-like peptide 1 receptor agonist that stimulates the GLP-1 receptor to increase glucosedependent insulin secretion, suppress glucagon release, and slow gastric emptying. Biguanides, of which metformin is the primary example, decrease hepatic glucose production, improve peripheral insulin sensitivity, and help lower blood glucose. This combination is often utilized when monotherapy is insufficient for glycemic control and has demonstrated efficacy in reducing hemoglobin A1c and promoting weight loss.

Brand names

Trulicity (for dulaglutide)Glucophage (for metformin, a main biguanide)

Other names

dulaglutidemetformin (main biguanide)