Drug intelligence / Profile preview

dulaglutide biosimilar 14028 injection

Development stage
Phase 1
Lead developer
Dongguan HEC Biopharmaceutical
Modality
Recombinant Proteins and Enzymes
Administration
Subcutaneous
01

Overview

Dulaglutide biosimilar, also known as "14028 injection" or "HEC14028", is a biosimilar to dulaglutide (Trulicity), a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist used for the treatment of type 2 diabetes mellitus. It's developed to match the pharmacokinetics, safety, and immunogenicity profile of Trulicity. Dulaglutide acts by binding to and activating the GLP-1 receptor, which increases insulin secretion in response to high blood glucose levels and suppresses glucagon secretion. This mechanism helps improve glycemic control in patients with type 2 diabetes. It was initially developed by Dongguan HEC Biopharmaceutical R&D Co., Ltd., with clinical studies sponsored by Sunshine Lake Pharma Co., Ltd.

Other names
14028 injectionHEC14028 injectionHEC-14028 injectionHEC 14028 injection
02

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