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Duolac

Development stage: Unknown
Lead developer: Cell Biotech
Modality: Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration: Oral

Overview

Duolac is a multi-strain probiotic supplement containing a combination of lactic acid bacteria (LAB), including *Streptococcus thermophilus*, *Lactobacillus acidophilus*, *Bifidobacterium lactis*, *Lactobacillus rhamnosus*, *Bifidobacterium longum*, and *Bifidobacterium bifidum*. It utilizes a patented dual-coating technology designed to protect the bacteria from gastric acid, bile salts, heat, and moisture, ensuring high survival rates and effective colonization in the intestine. Developed and investigated by Kosin University Gospel Hospital and manufactured by Cell Biotech, Duolac has been studied in clinical trials for its ability to restore gut microbiota and alleviate abdominal symptoms following colonoscopy bowel preparation, as well as for managing conditions like inflammatory bowel disease (IBD) and maintaining general gastrointestinal health.

Brand names: Duolac

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