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DuraLife Saffron
- Development stage
- Unknown
- Lead developer
- Faran Shimi
- Administration
- Oral
01
Overview
DuraLife Saffron is a dietary supplement (nutraceutical) developed and marketed by the Iranian pharmaceutical company Faran Shimi. The product contains standardized saffron extract (*Crocus sativus*), which is rich in bioactive compounds such as crocin, crocetin, and safranal. These constituents are believed to exert antidepressant and anxiolytic effects by modulating neurotransmitter levels in the brain, specifically by inhibiting the reuptake of serotonin, dopamine, and norepinephrine. It is typically indicated for the management of mild-to-moderate depression, anxiety, and premenstrual syndrome (PMS).
- Brand names
- DuraLife Saffron
- Other names
- saffron supplementCrocus sativus extract
02
Targets
SERT (Sodium-dependent serotonin transporter)SIGMAR1 (Sigma non-opioid intracellular receptor 1)AcetylcholinesteraseCYP3A4 (Cytochrome P450 3A4)NET (Norepinephrine Transporter)DAT (Dopamine plasma membrane transport protein)PTPN1 (Protein tyrosine phosphatase 1B)NMDAR (Glutamate receptor ionotropic, NMDA)
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