Drug intelligence / Profile preview

Durhalieve

Development stage
Discontinued
Lead developer
Echo Therapeutics
Modality
Small Molecules
Administration
Topical
01

Overview

Durhalieve is a topical corticosteroid formulation developed by Echo Therapeutics for the treatment of corticosteroid-responsive dermatoses. The product was a 1% hydrocortisone cream designed using a proprietary transdermal drug delivery technology intended to enhance skin penetration and efficacy. Echo Therapeutics submitted a New Drug Application (NDA) for Durhalieve to the FDA in late 2006. However, following a merger with Sontra Medical in 2007, the company shifted its strategic focus toward its needle-free continuous glucose monitoring (CGM) system (Symphony) and its skin preparation system (Prelude), leading to the discontinuation of the Durhalieve program before it reached the market.

Brand names
Durhalieve
Other names
hydrocortisone 1% topical
02

Targets

GR (Glucocorticoid receptor)

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