Drug intelligence / Profile preview

dust mite mixture

Development stage
Discontinued
Lead developer
Medi Trend
Modality
Sublingual Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Subcutaneous Immunotherapy → Allergy Immunotherapy → Therapeutic Vaccines → Vaccines & Immunotherapeutics
Administration
Sublingual
01

Overview

**Dust mite mixture** is a Zhejiang Wolwo Bio-Pharmaceutical allergen-specific immunotherapy product developed as a sublingual liquid drop formulation for dust-mite-induced allergic disease. Its active components are allergen proteins from *Dermatophagoides farinae* and *Dermatophagoides pteronyssinus*. The product completed a multicenter, randomized, double-blind, placebo-controlled Phase 2 study in moderate-to-severe perennial allergic rhinitis; Zhejiang Wolwo terminated further development of the program in November 2022 in favor of solid-form dust-mite allergen products. ([static.cninfo.com.cn](https://static.cninfo.com.cn/finalpage/2022-11-29/1215231021.PDF))

Other names
尘螨合剂尘螨合剂1号
02

Targets

IgE (Immunoglobulin E)MHC II (Major histocompatibility complex class II receptor)

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