Drug intelligence / Profile preview

DWC202101

Development stage
Unknown
Lead developer
Daewoong Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

DWC202101 is a specific formulation of metformin developed by Daewoong Pharmaceutical for the treatment of type 2 diabetes mellitus. As a biguanide antidiabetic agent, it primarily works by inhibiting hepatic gluconeogenesis (glucose production in the liver), decreasing intestinal absorption of glucose, and improving insulin sensitivity by increasing peripheral glucose uptake and utilization. In clinical development, DWC202101 has been studied as the metformin component for co-administration with the SGLT-2 inhibitor enavogliflozin (DWP16001) to evaluate pharmacokinetic equivalence and safety compared to their fixed-dose combination product, DWJ1525 (brand name Envlomet).

Other names
metformin
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)ND1 (Mitochondrial electron transport chain complex I)

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