Drug intelligence / Profile preview

DWJ1718

Development stage
Unknown
Lead developer
Great Bear Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

DWJ1718 is an investigational oral solid dosage form medication being developed by Daewoong Pharmaceutical (also known as Great Bear Pharmaceutical) for the treatment of Attention-Deficit/Hyperactivity Disorder (ADHD). It is classified as an incrementally modified drug (IMD), specifically a new formulation of methylphenidate hydrochloride. The drug is designed to provide a controlled or extended release of the active ingredient to improve therapeutic efficacy and patient adherence compared to existing formulations. DWJ1718 acts as a stimulant by inhibiting the reuptake of dopamine and norepinephrine in the central nervous system, thereby increasing their availability in the synaptic cleft. The program has progressed into Phase 3 clinical development in South Korea.

02

Targets

DAT (Dopamine plasma membrane transport protein)NET (Norepinephrine Transporter)

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