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Dynamic Chinese herbal granule formula
- Development stage
- Unknown
- Lead developer
- China Academy of Chinese Medical Sciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
The Dynamic Chinese herbal granule formula is an investigational Traditional Chinese Medicine (TCM) intervention developed by the China Academy of Chinese Medical Sciences for the treatment of ischemic stroke during the convalescent phase. This personalized therapeutic approach utilizes a set of 10 distinct herbal granules, which are combined and adjusted on a weekly basis by clinicians according to the patient's specific TCM syndrome differentiation (Zhenghou). The formula is designed to address the evolving clinical symptoms and physiological imbalances following a stroke, aiming to improve functional recovery and quality of life. As a multi-component therapy, its mechanism of action likely involves synergistic effects on neuroprotection, modulation of inflammatory responses, and improvement of cerebral microcirculation.
- Other names
- Dynamic Chinese herbal granule formulaFangjiDynamic Combination Therapy on Chinese Herbal Granules
02
Targets
TRPV4 (Transient receptor potential cation channel subfamily V member 4)P2RY1 (Purinergic Receptor P2Y1)NF-κBPTAFR (Platelet-activating factor receptor)GSK3 (Glycogen synthase kinase 3 beta)P2Y12 (Purinergic P2Y12 receptor)
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