Dyno-86m

Dyno-86m is an AI-designed adeno-associated virus (AAV) capsid optimized for gene therapy delivery to the eye via intravitreal injection. It was developed using generative artificial intelligence to enhance transduction efficiency and therapeutic gene delivery specifically targeting retinal cells. This capsid shows field-leading potential for non-invasive ocular gene therapies, enabling broader patient access compared to more invasive methods like subretinal injections. Dyno-86m is part of a platform of next-generation AAV vectors designed by Dyno Therapeutics aimed at improving delivery efficiency, manufacturability, and translatability from non-human primate models to humans in genetic medicine applications. It is available for licensing by gene therapy developers seeking advanced vector technology for eye diseases[1][3].