Drug intelligence / Profile preview

e-cue

Development stage
Unknown
Lead developer
Kaléo
Administration
Subcutaneous
01

Overview

**e-cue** is a novel epinephrine auto-injector developed by Intelliject for the emergency treatment of allergic reactions, including anaphylaxis. It delivers epinephrine, a sympathomimetic catecholamine that acts as an alpha- and beta-adrenergic agonist to rapidly reverse life-threatening symptoms by causing vasoconstriction, bronchodilation, increased cardiac output, and stabilization of mast cells to inhibit further mediator release. The device received tentative FDA approval for its NDA, indicating it met safety and efficacy standards pending final approval, likely related to manufacturing or patent exclusivity issues.[3]

Brand names
e-cue
02

Targets

ADRB2 (β2)ADRB1 (β1)ADRA2A (α2A)ADRA1A (α1A)

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