Drug intelligence / Profile preview

E0714

Development stage
Preclinical
Lead developer
Hebei Medical University
01

Overview

E0714: sourced facts only. name: "Electrophysiology assays demonstrated that E0714 potently activates Kv7.2 without significantly affecting Kv7.1, Kv7.3, Kv7.4, or Kv7.5." [PMID:41711326]; target: "Electrophysiology assays demonstrated that E0714 potently activates Kv7.2 without significantly affecting Kv7.1, Kv7.3, Kv7.4, or Kv7.5." [PMID:41711326]; developer: "School of Pharmacy, Hebei Medical University, Shijiazhuang 050017, China." [PMID:41711326]; stage: "E0714 exhibited an excellent antiepileptic effect in classical epilepsy models without causing motor coordination problems." [PMID:41711326]

02

Targets

KCNQ2 (Potassium voltage-gated channel subfamily KQT member 2)

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