Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
E10H autologous natural killer cell injection
- Development stage
- Phase 2
- Lead developer
- Guangzhou DoublleBioproduct
- Modality
- CAR-NK Cells → Other Engineered Cells → Adoptive Cell Transfer → Cell Therapies, Lymphokine-Activated Killer Cells → Native Immune Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
E10H is an autologous natural killer (NK) cell therapy developed by Guangzhou Doublle Bioproduct for the treatment of advanced gastrointestinal cancers, including gastric adenocarcinoma, gastroesophageal junction adenocarcinoma, and colorectal cancer. As a non-genetically modified autologous cell therapy, E10H is prepared by isolating NK cells from a patient's peripheral blood, expanding and activating them ex vivo, and then reinfusing them into the patient. Once reinfused, these activated NK cells leverage innate immune mechanisms to target and eliminate tumor cells. E10H is currently in Phase II clinical development in China, where it is being evaluated as a first-line treatment in combination with IgG1 antibodies and chemotherapy.
- Other names
- Autologous Natural Killer Cell Injection自体自然杀伤细胞注射液
Beyond the preview
Go deeper on E10H autologous natural killer cell injection.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on E10H autologous natural killer cell injection.