Drug intelligence / Profile preview

EA501

Development stage
Preclinical
Lead developer
Suzhou Bowei Biotechnology
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravitreal, Ophthalmic
01

Overview

EA501 is a preclinical-stage monoclonal antibody being developed by Neathera (also known as Shanghai EA Therapeutics or Shandong Lanyi Pharmaceutical Technology) for the treatment of ophthalmologic conditions, including diabetic eye disease, age-related macular degeneration (AMD), and geographic atrophy. The drug is designed to modulate both the complement pathway and angiogenesis, addressing key pathological drivers of retinal diseases. EA501 is currently in preclinical development, with Phase I/II clinical trials targeted to begin in 2027.

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