Drug intelligence / Profile preview

Ear Comfort

Development stage
Unknown
Lead developer
Now Foods
Modality
Small Molecules
Administration
Topical
01

Overview

Ear Comfort is a multi-ingredient topical herbal oil formulation, most notably produced by NOW Foods, designed to support ear health and alleviate minor irritation. The product is a combination of botanical extracts, including Mullein (Verbascum thapsus), Calendula (Calendula officinalis), St. John's Wort (Hypericum perforatum), and Garlic (Allium sativum). These ingredients are traditionally recognized for their antimicrobial, anti-inflammatory, and analgesic properties. The formulation is typically delivered in a base of extra virgin olive oil, often enriched with Vitamin E and Tea Tree oil to provide emollient effects and enhance the stability of the active components. While marketed as a dietary supplement or nutraceutical, it is used topically in the ear canal to soothe the lining and provide a protective environment against environmental irritants.

Brand names
Ear Comfort
Other names
NOW Ear ComfortSimilasan Ear Comfort
02

Targets

PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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