EB 1213

EB 1213 is a synthetic vitamin D analog, a small molecule with the molecular formula C31H44O4. It functions by binding to the intracellular vitamin D receptor (VDR) and is more efficient than 1alpha,25-dihydroxyvitamin D3 (1alpha,25[OH]2D3) in inducing VDR transcription. In preclinical studies, EB 1213 demonstrated potent anti-proliferative and differentiation-inducing effects on human skin cells in vitro, suggesting its potential for conditions like psoriasis.

Other names

(5Z,7E)-(1S,3R)-23-oxa-23-[3-(1-hydroxy-1-methylethyl)phenyl]-24,25,26,27-tetranor-9,10-seco-5,7,10(19)-cholestatriene-1,3-diol(5Z,7E)-(1S,3R)-23-oxa-23-(3-(1-hydroxy-1-methylethyl)phenyl)-24,25,26,27-tetranor-9,10-seco-5,7,10(19)-cholestatriene-1,3-diolRefChem:920791(1R,3S,5Z)-5-[(2E)-2-[(1R,3As,7aR)-1-[(2S)-1-[3-(2-hydroxypropan-2-yl)phenoxy]propan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diolCHEBI:168812LMST03020682LMST-03020682LMST 03020682