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ebola vaccine + marburg vaccine + lassa vaccine
- Development stage
- Unknown
- Lead developer
- Aurobindo Pharma
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
A trivalent viral vector vaccine candidate designed to provide protection against Ebola virus, Marburg virus, and Lassa virus. The vaccine utilizes the VesiculoVax platform, which is based on an attenuated Vesicular Stomatitis Virus (VSV) vector engineered to express the surface glycoproteins of the three target pathogens. By delivering these antigens, the vaccine aims to elicit both neutralizing antibody and cellular immune responses against these high-consequence viral hemorrhagic fevers. Originally developed by Profectus BioSciences, the program was licensed by Emergent BioSolutions for further development and commercialization as part of their strategic focus on public health threats.
- Other names
- trivalent VesiculoVax vaccineEbola/Marburg/Lassa vaccine
02
Targets
PYG (Glycogen phosphorylase)GPC (Lassa virus glycoprotein complex)Zaire ebolavirus glycoprotein
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