Drug intelligence / Profile preview

echinacea purpurea leaf extract

Development stage
Preclinical
Lead developer
Nativital Doğal Yaşam ve Sağlık Ürünleri
Modality
Small Molecules, Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

Echinacea purpurea leaf extract is a botanical preparation derived from the leaves of the purple coneflower (*Echinacea purpurea* L.). It is characterized by a high concentration of phenolic compounds, specifically hydroxycinnamic acids such as chicoric, caftaric, and chlorogenic acids. The extract exhibits significant anti-inflammatory properties by inhibiting the production of pro-inflammatory mediators, including Interleukin-6 (IL-6), Interleukin-8 (IL-8), and Prostaglandin E2 (PGE2). Research indicates that these effects are particularly relevant for intestinal health, as the extract's bioactivity is partially maintained following simulated gastrointestinal digestion. It is primarily investigated for its potential in treating inflammatory bowel diseases (IBD), ulcerative colitis, and other gastrointestinal inflammatory conditions.

Other names
purple coneflower leaf extractEchinacea purpurea leaves extract
02

Targets

IL-6 (Interleukin 6)IL8 (C-X-C Motif Chemokine Ligand 8)PGE2 (Prostaglandin E2)

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