Drug intelligence / Profile preview

echinops cephalotes hydroalcoholic extract

Development stage
Preclinical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

**Echinops cephalotes hydroalcoholic extract** is a plant-derived botanical extract prepared from *Echinops cephalotes* and studied primarily as an academic research compound rather than a commercial pharmaceutical asset. In preclinical Alzheimer's disease models, particularly scopolamine-induced memory impairment in mice, the extract has shown cognition-improving activity associated with anti-cholinesterase and anti-butyrylcholinesterase effects, consistent with enhancement of central cholinergic signaling. Reported studies evaluated oral doses such as 25, 50, and 100 mg/kg in mice. Beyond neurocognitive research, extracts of *Echinops cephalotes* have also been investigated experimentally for antidiabetic, cardioprotective, and antifungal properties, but there is no identified branded product, commercial manufacturer, or named company-led development program for this specific hydroalcoholic extract.

Other names
Echinops cephalotes hydroalcoholic extractEC hydroalcoholic extract
02

Targets

ButyrylcholinesteraseAcetylcholinesterase

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