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echium amoenum extract
- Development stage
- Unknown
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Echium amoenum extract is a botanical product derived from the dried flowers of *Echium amoenum*, a medicinal plant native to Iran. The extract contains active phenolic compounds, including rosmarinic acid and anthocyanins such as cyanidin-3-glucoside and delphinidin. It exerts therapeutic effects through multiple mechanisms, including antioxidant activity, inhibition of acetylcholinesterase, and anti-inflammatory actions via the suppression of cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS), and pro-inflammatory cytokines. Clinical research has investigated its efficacy in treating obsessive-compulsive disorder (OCD), generalized anxiety disorder (GAD), and mild to moderate depression, while preclinical models suggest potential benefits in Alzheimer's disease and pain management.
- Other names
- echium amoenum extractEchium amoenum aqueous extractEchium amoenum hydroalcoholic extractGol-e-Gavzaban extract
02
Targets
AcetylcholinesteraseNOS2 (Nitric Oxide Synthase 2)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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