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Echiven
- Development stage
- Unknown
- Lead developer
- VINS Bio Products
- Modality
- Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
Echiven is an equine-derived monovalent antivenom developed by VINS Bio Products for the treatment of snake envenomation caused by the West African saw-scaled viper (*Echis ocellatus*). It consists of purified F(ab')2 antibody fragments obtained from the plasma of horses immunized against *Echis ocellatus* venom. The polyclonal antibodies in Echiven physically bind to and neutralize the active toxins within the venom, preventing systemic toxicity and tissue damage. It is approved and marketed in several sub-Saharan African countries where *Echis ocellatus* envenomation is a major public health concern.
- Brand names
- Echiven
- Other names
- Snake Venom Antiserum (Echiven)Snake Venom Antiserum EchisSnake Venom Antiserum Echis OcellatusVINS-Echis
02
Targets
EoVMPs (Echis ocellatus venom metalloproteinases)Venoms/toxins from related Echis speciesSVSP (Snake venom serine protease)svPLA2 (Echis ocellatus venom phospholipase A2 toxins)
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