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econazole nitrate + mometasone furoate
- Development stage
- Unknown
- Lead developer
- Sol-Gel Technologies
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
S2G6T-1 is a topical combination drug candidate developed by Sol-Gel Technologies for the treatment of symptomatic inflammatory interdigital tinea pedis (athlete's foot). It consists of econazole nitrate, a broad-spectrum imidazole antifungal agent, and mometasone furoate, a potent synthetic corticosteroid. The combination is designed to simultaneously treat the underlying fungal infection and alleviate associated inflammatory symptoms such as pruritus, erythema, and swelling. The product likely utilizes Sol-Gel's proprietary silica-based microencapsulation technology to optimize the stability and delivery of the active ingredients. In clinical studies, S2G6T-1 has been compared against its individual monads (econazole nitrate and mometasone furoate) and a vehicle control to assess its efficacy and safety in patients aged 12 years and older.
- Other names
- econazole nitrate / mometasone furoate
02
Targets
GR (Glucocorticoid receptor)CYP51A1 (Sterol 14α-demethylase)
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