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EDI-M405 is a preclinical-stage vaccine candidate developed by the Empire Discovery Institute (EDI). It is designed to induce an immune response against antigens from *Moraxella catarrhalis*, a common respiratory pathogen. The primary indications for EDI-M405 are the prevention and treatment of exacerbations in Chronic Obstructive Pulmonary Disease (COPD) and the prevention of Otitis Media (middle ear infections) in children. *M. catarrhalis* is a significant contributor to the inflammatory burden in these conditions, and a successful vaccine could reduce antibiotic usage and disease morbidity.
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