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EDP172

Development stage: Preclinical
Lead developer: Genor Biopharma
Modality: Chemically Modified siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Conjugated siRNA → Small Interfering RNA (siRNA) → Small RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics

Overview

EDP172 is a dual-targeting small interfering RNA (siRNA) therapeutic being developed by Genor Biopharma for the treatment of hyperlipidemia and atherosclerotic cardiovascular disease (ASCVD). The drug is designed to simultaneously silence two distinct genetic targets involved in lipid metabolism or cardiovascular risk reduction, utilizing the RNA interference (RNAi) pathway to degrade messenger RNA (mRNA) transcripts and prevent the translation of proteins that contribute to elevated lipid levels. EDP172 is part of Genor Biopharma's oligonucleotide platform, which focuses on cardiometabolic and liver diseases.

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