Drug intelligence / Profile preview

EG201

Development stage
Preclinical
Lead developer
Elisigen
Modality
Gene Addition/Replacement → Gene Therapies, Gene Editing → Gene Therapies, Gene Silencing → Gene Therapies
Administration
Intrathecal
01

Overview

EG201 is a preclinical-stage gene therapy candidate being developed by Elisigen for the treatment of chronic neuropathic pain. The therapy utilizes an adeno-associated virus (AAV) vector to deliver a therapeutic genetic payload designed to modulate pain signaling pathways in the peripheral nervous system. By targeting the underlying molecular mechanisms of neuropathic pain, EG201 aims to provide long-lasting analgesia through a single administration, potentially offering a safer and more effective alternative to traditional systemic pharmacological treatments such as opioids or anticonvulsants. The program is part of Elisigen's broader pipeline of AAV-based gene silencing therapies for neurological and pain disorders.

02

Targets

FAM19A5 (Family with Sequence Similarity 19 Member A5)

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