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Egg phospholipids

Development stage
Unknown
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intravenous
01

Overview

Egg phospholipids are a purified mixture of naturally occurring phospholipids isolated from the yolk of eggs. They are primarily composed of about 78–80% phosphatidylcholine (PC), with additional components including phosphatidylethanolamine (PE), sphingomyelin (SM), lysophosphatidylcholine (LPC), lysophosphatidylethanolamine (LPE), plasmalogen and minor amounts of other lipids[2][5][6]. Egg phospholipids are used as an intravenous fat emulsion to provide a source of calories for patients requiring parenteral nutrition[2][3]. In pharmaceutical formulations they serve as emulsifiers and carriers due to their high biocompatibility and amphiphilic properties[1][4][5]. Their mechanism is not pharmacological in the traditional sense; rather they act as structural lipids supporting cell membrane integrity and function. They also play roles in drug delivery systems such as liposomes and micelles for improved bioavailability and stability of drugs[4][5].

Brand names
Omegaven EmulsiyonPuralor
Other names
Lecithins egg yolkPhospholipids egg
02

Targets

PPARA (Peroxisome proliferator-activated receptor alpha)Lipid bilayer

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