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Egg yolk protein extract is a biological substance derived from the yolks of chicken eggs, often utilized for its functional protein content, including Immunoglobulin Y (IgY). In the context of gastrointestinal health, specifically regarding *Helicobacter pylori* infection, these extracts are typically produced from hens immunized against *H. pylori* antigens. The resulting IgY antibodies within the extract bind to the bacteria's surface components, such as urease or adhesins, thereby preventing their attachment to the gastric epithelial cells and reducing colonization. This extract is being investigated in clinical trials, such as the Phase 0 study ChiCTR2400092806, to evaluate its efficacy in improving gastric function and modulating the gut microbiota in infected individuals.
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