Drug intelligence / Profile preview

eicosapentaenoic acid + docosahexaenoic acid

Development stage
Approved
Lead developer
BASF
Modality
Small Molecules
Administration
Oral
01

Overview

Eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are long-chain omega-3 polyunsaturated fatty acids commonly found together in marine oils such as fish oil. This combination is used as a dietary supplement and sometimes as a prescription medication to lower triglyceride levels and support cardiovascular health. EPA and DHA are essential components of cell membranes, especially in the brain, retina, and sperm. They serve as precursors for eicosanoids—signaling molecules that regulate inflammation, platelet aggregation, vasodilation/vasoconstriction, and other physiological processes. Clinical evidence supports their use in reducing triglycerides; they may also have benefits for heart disease prevention, cognitive function during development and aging, rheumatoid arthritis symptom relief, eye health (macular degeneration), blood pressure reduction in some populations, migraine relief, asthma symptom reduction due to anti-inflammatory effects on leukotrienes/cytokines/eicosanoids[2][4][5][6].

Brand names
LovazaOmacorOmega-3-Dha-Epa-Fish OilOmega3-Dha-Epa-Fish OilOmega 3-Dha-Epa-Fish Oil
Other names
EPA + DHAomega-3 fatty acids (marine)fish oil (EPA/DHA combination)
02

Targets

15-LOX (Lysyl Oxidase)COXCYP2J2 (Cytochrome P450 family 2 subfamily J member 2)

Beyond the preview

Go deeper on eicosapentaenoic acid + docosahexaenoic acid.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on eicosapentaenoic acid + docosahexaenoic acid.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call