Drug intelligence / Profile preview

eicosapentaenoic acid + alpha-lipoic acid

Development stage
Unknown
Administration
Oral, Intravenous
01

Overview

A combination of eicosapentaenoic acid (EPA), an omega-3 fatty acid found in cold-water fish, and alpha-lipoic acid (ALA), a naturally occurring antioxidant. This combination has been studied for weight management, reducing inflammation, and improving cardiovascular health markers. EPA contributes anti-inflammatory properties and helps maintain leptin levels during weight loss, while ALA provides antioxidant effects and may directly promote weight loss. Clinical studies suggest this combination may be particularly effective for overweight or obese individuals following energy-restricted diets.

Other names
eicosapentaenoic acid and alpha-lipoic acidEPA + ALAEPA + α-lipoic acid
02

Targets

OADHCs (Mitochondrial 2-oxoacid dehydrogenase complexes)LEPR (Leptin receptor)

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