Drug intelligence / Profile preview

eicosapentaenoic acid + astaxanthin + tocotrienol

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

A combination dietary supplement composed of **eicosapentaenoic acid (EPA)**, **astaxanthin**, and **tocotrienol**. EPA is an omega-3 fatty acid known for its cardiovascular, triglyceride-lowering, and anti-inflammatory properties. Astaxanthin is a xanthophyll carotenoid with potent antioxidant and anti-inflammatory effects. Tocotrienol is a member of the vitamin E family that exhibits antioxidant, cholesterol-lowering, neuroprotective, and anti-cancer activities. The combination is designed to provide enhanced anti-inflammatory and antioxidant effects, with research suggesting possible synergistic actions, including reduced production of inflammatory markers (such as nitric oxide and cytokines), and increased cell viability in immune cells compared to single-component treatments. It is primarily marketed as a dietary supplement aimed at supporting cardiovascular, metabolic, and inflammatory health[1][4][5][6]. No pharmaceutical (prescription or OTC drug) formulation containing this exact combination is currently approved.

02

Targets

PPARA (Peroxisome proliferator-activated receptor alpha)LDLR (Low-density lipoprotein receptor)NF-κB

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