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ELI-301 is a preclinical-stage theranostic radiopharmaceutical developed by Eli Radiopharma for the treatment and imaging of solid tumors. It is designed as a versatile platform that can be labeled with different radionuclides depending on the clinical requirement: Gallium-68 (⁶⁸Ga) for diagnostic PET imaging, or Lutetium-177 (¹⁷⁷Lu) and Actinium-225 (²²⁵Ac) for targeted radiotherapy. By utilizing these isotopes, ELI-301 aims to provide a "see-and-treat" approach, allowing for the identification of tumor lesions and subsequent delivery of therapeutic radiation. The specific molecular target of the ELI-301 ligand has not been disclosed by the sponsor.
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