Drug intelligence / Profile preview

elvucitabine

Development stage
Phase 2
Lead developer
Alexion Pharmaceuticals
Modality
Small Molecules
Administration
Oral
01

Overview

Elvucitabine is an investigational nucleoside reverse transcriptase inhibitor (NRTI) developed for the treatment of HIV infection. It is a cytidine analog that inhibits HIV-1 reverse transcriptase by competing with natural substrates and causing chain termination during viral DNA synthesis. Elvucitabine was designed to have activity against both wild-type and certain drug-resistant strains of HIV. The drug was developed by Achillion Pharmaceuticals and has undergone clinical trials for use in combination antiretroviral therapy regimens.

Other names
2',3'-dideoxy-2',3'-didehydro-beta-L-5-fluorocytidine
02

Targets

Human immunodeficiency virus type 1 reverse transcriptase

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