Drug intelligence / Profile preview

EM1042

Development stage
Preclinical
Lead developer
EpimAb Biotherapeutics
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

EM1042 is a preclinical bispecific antibody candidate developed by EpimAb Biotherapeutics for the treatment of autoimmune diseases, specifically those involving inflammatory cells. Developed using EpimAb's proprietary FIT-Ig (Fabs-In-Tandem Immunoglobulin) platform, EM1042 functions as a T-cell engager (TCE). While the specific molecular targets are currently undisclosed by the developer, the therapeutic strategy involves leveraging T-cell engagement to modulate or deplete specific inflammatory cell populations responsible for autoimmune pathology. This approach represents an expansion of T-cell engager technology, which is traditionally used in oncology, into the field of immunology and inflammatory disorders.

02

Targets

CD3 (T-cell surface glycoprotein CD3)

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