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EMD-386088
- Development stage
- Unknown
- Lead developer
- Boehringer
- Modality
- Small Molecules
- Administration
- Intraperitoneal, Intrahippocampal
01
Overview
EMD-386088 is a tetrahydropyridinylindole derivative primarily utilized in scientific research. It functions as a potent partial agonist of the 5-HT6 receptor. Additionally, it acts as a dopamine reuptake inhibitor, an action believed to contribute to its antidepressant-like effects observed in rodent studies.
- Other names
- 5-chloro-2-methyl-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole
02
Targets
HTR6 (5-hydroxytryptamine receptor 6)HTR4 (5-Hydroxytryptamine receptor 4)HTR3A (5-hydroxytryptamine receptor 3A)HTR1B (5-Hydroxytryptamine Receptor 1B)HTR1D (5-hydroxytryptamine receptor 1D)HTR2A (Serotonin receptor 5-HT2A)HTR7 (5-hydroxytryptamine receptor 7)HTR2C (5-hydroxytryptamine 2C receptor)DAT (Dopamine plasma membrane transport protein)HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))
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