Drug intelligence / Profile preview

Emluz

Development stage
Unknown
Lead developer
Emcutix Biopharmaceuticals
Modality
Small Molecules
Administration
Topical
01

Overview

Emluz is a topical antifungal cream containing 1% luliconazole, developed and marketed by Emcutix Biopharmaceuticals, a subsidiary of Emcure Pharmaceuticals. It is indicated for the treatment of various fungal skin infections, including tinea pedis (athlete's foot), tinea corporis (ringworm), and tinea cruris (jock itch). Luliconazole, an imidazole antifungal, works by inhibiting the enzyme lanosterol 14-alpha-demethylase, which is essential for the synthesis of ergosterol, a key component of fungal cell membranes. This disruption leads to increased membrane permeability and fungal cell death. Emluz is available as a topical cream in 20g and 40g tubes and is approved for use in India.

Brand names
Emluz
Other names
luliconazole
02

Targets

CYP51A1 (Sterol 14α-demethylase)

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