Drug intelligence / Profile preview

emollient + topical corticosteroids

Development stage
Unknown
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

A combination therapy of emollients and topical corticosteroids is widely used in dermatology, particularly for the management of inflammatory skin conditions such as eczema, dermatitis, and psoriasis. Emollients are moisturizing agents that soothe, soften, and hydrate the skin by forming an occlusive barrier to prevent water loss. Topical corticosteroids are anti-inflammatory agents that reduce redness, swelling, itching, and irritation by suppressing local immune responses in the skin. The combination is not a single fixed pharmaceutical product but rather a regimen where both types of products are applied—often with emollients used to maintain hydration and barrier function while topical corticosteroids control inflammation during flare-ups. This approach helps maximize symptom relief while minimizing potential side effects from prolonged steroid use[1][2][3][5].

Other names
emollients and corticosteroidstopical corticosteroids and emollientsmoisturizers and corticosteroids
02

Targets

GR (Glucocorticoid receptor)Stratum corneum lipid matrix

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