Drug intelligence / Profile preview

ENA-003

Development stage
Unknown
Lead developer
Enalare Therapeutics
Modality
Small Molecules
01

Overview

ENA-003 is a small molecule opioid receptor antagonist being developed by Enalare Therapeutics for the treatment of drug overdose-induced respiratory depression. The drug is designed to reverse or prevent the life-threatening suppression of breathing caused by opioids. Currently in Phase 2 clinical development, ENA-003 represents a potential therapeutic option for emergency intervention in opioid overdose scenarios, aiming to restore normal ventilatory function by blocking the effects of opioids at their receptor sites.

02

Targets

MOR (Mu opioid receptor)

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